Stay plugged into Penn with this daily newsletter rounding up all of the top headlines from top headlines Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. The week's top stories from the DP and beyond, meticulously curated for parents and alumni, and delivered This study is the first published case where researchers identified a specific target and reduced the levels solely in the mitochondria and no other parts of the cell. Office of University Communications Suite 200 3901 Walnut Street Philadelphia, PA 19104-3608 Xiaolu Ang Cambronne, PhD, an assistant professor in the department of Molecular Biosciences in The University of Texas at Austin, served as co-senior author. The work is in its early days, but a door has been opened for new investigations centered on mitochondrial NAD+ and this gene. Free. campus culture and arts scene. The Perelman School of Medicine has been ranked among the top medical schools in the United States for more than 20 years, according to U.S. News & World Report's survey of research-oriented medical schools. James Tonrey | Annenberg study reveals American civic knowledge increased since last year, James Tonrey | Pennsylvania's COVID-19 death toll may double by January, new model suggests. This story is by Frank Otto. PHILADELPHIA — Penn Medicine researchers have solved a decades old mystery around a key molecule fueling the power plant of cells that could be exploited to find new ways to treat diseases, from neurodegenerative disorders to cancer. A Spanish language version launched in May has enrolled more than 140 patients, Penn Medicine News reported.. Penn Medicine will utilize the PCORI grant to determine if the COVID Watch program reduces disparities in care among Black and Latinx patients by providing greater access to telemedicine among … Free. delivered directly to your inbox. Like the other vaccine innovations that arose from Penn research, the origin of mRNA vaccines also has Penn ties. Authors on the study from Penn include lead author Timothy S. Luongo, co-authors Caroline Perry, Marc R. Bornstein, F. Brad Johnson and corresponding author, Joseph A. Baur. The study’s authors found that the readmission rate was about twice that of other infectious diseases, Penn Medicine News reported. During the first three months of Philadelphia’s COVID-19 outbreak, 4.7% of people sent home after an initial emergency room visit for coronavirus returned to the hospital within just three days. NAD+ is a fundamental molecule required for maintaining the mitochondrial-mediated energy production. According to data collected during the first three months of Philadelphia’s COVID-19 outbreak, 4.7% of people sent home after an initial emergency room visit for coronavirus returned to the hospital within just three days, Penn Medicine News reported. Several hypotheses had been circulating, including the idea that mammalian mitochondria were incapable of NAD+ transport, instead relying entirely on synthesis of NAD+ within the organelle, but in 2018, Baur’s lab put that idea to rest when it reported in an eLife study that a transporter was in fact responsible. Two of Pardi’s mentors, Drew Weissman and Katalin Kariko, both of Penn Medicine, began working together in the late-1990s to use RNA for therapy, publishing several landmark papers over the ensuing two decades.